ARG55470

anti-AKR1B1 antibody

anti-AKR1B1 antibody for ICC/IF,Western blot and Human,Mouse,Rat

Metabolism antibody; Signaling Transduction antibody

概述

产品描述 Rabbit Polyclonal antibody recognizes AKR1B1
反应物种 Hu, Ms, Rat
应用 ICC/IF, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 AKR1B1
抗原物种 Human
抗原 Recombinant protein of Human AKR1B1 (NP_001619.1)
偶联标记 Un-conjugated
別名 Aldo-keto reductase family 1 member B1; Aldose reductase; ALR2; ALDR1; AR; Aldehyde reductase; EC 1.1.1.21; ADR

应用说明

预测反应性说明 Rat
应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Mouse heart and HepG2
实际分子量 ~ 36 kDa

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 231 Human AKR1B1

GeneID: 24192 Rat AKR1B1

Swiss-port # P07943 Rat Aldose reductase

Swiss-port # P15121 Human Aldose reductase

基因名称 AKR1B1
全名 aldo-keto reductase family 1, member B1 (aldose reductase)
背景介绍 This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
生物功能 Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. [UniProt]
研究领域 Metabolism antibody; Signaling Transduction antibody
预测分子量 36 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG55470 anti-AKR1B1 antibody WB image

    Western blot: Mouse heart and HepG2 cell lysates stained with ARG55470 anti-AKR1B1 antibody.