ARG41194
anti-AKAP7 antibody
anti-AKAP7 antibody for Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes AKAP7 |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AKAP7 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-81 of Human AKAP7 (NP_004833.1). |
| 偶联标记 | Un-conjugated |
| 別名 | AKAP15; AKAP-7 isoform gamma; A-kinase anchor protein 18 kDa; PRKA7 isoform gamma; A-kinase anchor protein 7 isoform gamma; Protein kinase A-anchoring protein 7 isoform gamma; AKAP 18; AKAP18 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse brain | ||||
| 实际分子量 | 14 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O55074 Mouse A-kinase anchor protein 7 isoform alpha |
|---|---|
| 基因名称 | AKAP7 |
| 全名 | A kinase (PRKA) anchor protein 7 |
| 背景介绍 | This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Apr 2011] |
| 生物功能 | Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm. [UniProt] |
| 预测分子量 | 40 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG41194 anti-AKAP7 antibody WB image
Western blot: 25 µg of Mouse brain lysate stained with ARG41194 anti-AKAP7 antibody at 1:3000 dilution.
