ARG64102
anti-AIRE antibody
anti-AIRE antibody for Western blot and Human,Mouse
Gene Regulation antibody; Immune System antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes AIRE |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Cow, Rat, Pig |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AIRE |
| 抗原物种 | Human |
| 抗原 | C-KAKPPKKPESSAEQ |
| 偶联标记 | Un-conjugated |
| 別名 | APECED; Autoimmune regulator; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; AIRE1; PGA1; APECED protein |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012] |
| 研究领域 | Gene Regulation antibody; Immune System antibody |
| 预测分子量 | 58 kDa |
| 翻译后修饰 | Phosphorylated. Phosphorylation could trigger oligomerization. |
检测图片 (1) Click the Picture to Zoom In
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ARG64102 anti-AIRE antibody WB image
Western Blot: human spleen lysate (35 µg protein in RIPA buffer) stained with ARG64102 anti-AIRE (isoforms 1 + 2) antibody at 0.3 µg/ml dilution.
