ARG66883
anti-AIFM2 / AMID antibody
anti-AIFM2 / AMID antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Monkey
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes AIFM2 / AMID |
|---|---|
| 反应物种 | Hu, Mk |
| 预测物种 | Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AIFM2 / AMID |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 141-190 of Human AIFM2 / AMID. |
| 偶联标记 | Un-conjugated |
| 別名 | AMID; Apoptosis-inducing factor-like mitochondrion-associated inducer of death; p53-responsive gene 3 protein; PRG3; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; Apoptosis-inducing factor 2 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Tris/EDTA buffer (pH 8.0) at high pressure and temperature. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | COS7 | ||||||
| 实际分子量 | ~ 41 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AIFM2 |
| 全名 | apoptosis-inducing factor, mitochondrion-associated, 2 |
| 背景介绍 | This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor protein p53 in colon cancer cells. [provided by RefSeq, Nov 2010] |
| 生物功能 | Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest. [UniProt] |
| 细胞定位 | Cytoplasm. Mitochondrion outer membrane. Membrane; Lipid-anchor. [UniProt] |
| 预测分子量 | 41 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG66883 anti-AIFM2 / AMID antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human lung cancer tissue. Antigen Retrieval: Tris/EDTA buffer (pH 8.0) at high pressure and temperature. The tissue section was stained with ARG66883 anti-AIFM2 / AMID antibody at 1:100 dilution, overnight at 4°C. Negetive control (right): Antibody was pre-absorbed by immunogen peptide.
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ARG66883 anti-AIFM2 / AMID antibody WB image
Western blot: COS7 cell lysate stained with ARG66883 anti-AIFM2 / AMID antibody.
