ARG64575

anti-AID antibody

anti-AID antibody for Western blot and Human

Gene Regulation antibody; Immune System antibody

概述

产品描述 Goat Polyclonal antibody recognizes AID
反应物种 Hu
预测物种 Cow, Pig
应用 WB
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 AID
抗原物种 Human
抗原 RRKFLYQFKNVR-C
偶联标记 Un-conjugated
別名 Cytidine aminohydrolase; CDA2; HIGM2; Activation-induced cytidine deaminase; AID; EC 3.5.4.38; ARP2; Single-stranded DNA cytosine deaminase; HEL-S-284

应用说明

应用建议
应用 推荐稀释比
WB0.1 - 0.3 µg/ml
应用说明 WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 57379 Human AICDA

Swiss-port # Q9GZX7 Human Single-stranded DNA cytosine deaminase

背景介绍 This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]
研究领域 Gene Regulation antibody; Immune System antibody
预测分子量 24 kDa
翻译后修饰 Ser-38 is the major site whereas Thr-27 is the minor site of phosphorylation. Phosphorylation regulates its class-switch recombination activity.
Probably monoubiquitinated on several residues by RNF126.

检测图片 (1) Click the Picture to Zoom In

  • ARG64575 anti-AID antibody WB image

    Western Blot: Human Tonsil lysate (35 µg protein in RIPA buffer) stained with ARG64575 anti-AID antibody at 0.1 µg/ml dilution.