概述

产品描述	Rabbit Polyclonal antibody recognizes AGTRAP
反应物种	Hu, Ms, Rat
应用	ICC/IF, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	AGTRAP
抗原物种	Human
抗原	Recombinant Protein of Human AGTRAP.
偶联标记	Un-conjugated
別名	ATRAP; Type-1 angiotensin II receptor-associated protein; AT1 receptor-associated protein

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	BxPC-3

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 11610 Mouse AGTRAP GeneID: 298646 Rat AGTRAP GeneID: 57085 Human AGTRAP Swiss-port # Q642A2 Rat Type-1 angiotensin II receptor-associated protein Swiss-port # Q6RW13 Human Type-1 angiotensin II receptor-associated protein Swiss-port # Q9WVK0 Mouse Type-1 angiotensin II receptor-associated protein More
基因名称	AGTRAP
全名	angiotensin II receptor-associated protein
背景介绍	This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
生物功能	Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. [UniProt]
预测分子量	17 kDa

检测图片 (1) Click the Picture to Zoom In