ARG64140
anti-AGTR1 / AT1 antibody
anti-AGTR1 / AT1 antibody for Western blot and Human,Mouse
Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes AGTR1 / AT1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 特异性 | All reported variants represent identical protein (NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1 and NP_114438.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AGTR1 / AT1 |
| 抗原物种 | Human |
| 抗原 | C-EIQKNKPRNDDIFK |
| 偶联标记 | Un-conjugated |
| 別名 | AT1AR; Angiotensin II type-1 receptor; AT1R; Type-1 angiotensin II receptor; AT1BR; AG2S; AT2R1; HAT1R; AT1; AGTR1B; AT1B |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012] |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody |
| 预测分子量 | 41 kDa |
| 翻译后修饰 | C-terminal Ser or Thr residues may be phosphorylated. |
检测图片 (1) Click the Picture to Zoom In
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ARG64140 anti-AGTR1 / AT1 antibody WB image
Western Blot: Mouse Liver lysate (35 µg protein in RIPA buffer) stained with ARG64140 anti-AGTR1 / AT1 antibody at 0.3 µg/ml dilution.
