ARG45333
anti-AGRP / Agouti related protein antibody [32B12]
anti-AGRP / Agouti related protein antibody [32B12] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody [32B12] recognizes AGRP / Agouti related protein |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 32B12 |
| 同位型 | IgG2 |
| 靶点名称 | AGRP / Agouti related protein |
| 抗原物种 | Human |
| 抗原 | Recombinant Human AGRP / Agouti related protein. |
| 偶联标记 | Un-conjugated |
| 別名 | Agouti-related protein; AGRT; ART; ASIP2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G chromatography |
| 缓冲液 | PBS |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AGRP |
| 全名 | Agouti Related Neuropeptide |
| 背景介绍 | This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009] |
| 生物功能 | Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. [UniProt] |
| 细胞定位 | Golgi apparatus; Secreted. [UniProt] |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | Disulfide bond. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG45333 anti-AGRP / Agouti related protein antibody [32B12] IHC-P image
Immunohistochemistry: Human placental stained with ARG45330 anti-Inhibin beta B antibody [9M29].
