ARG44619
anti-AGR3 antibody
anti-AGR3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes AGR3 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | AGR3 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | AGR3; Anterior Gradient 3, Protein Disulphide Isomerase Family Member; BCMP11; PDIA18; HAG-3; Protein Disulfide Isomerase Family A, Member 18; Breast Cancer Membrane Protein 11; HAG3; Anterior Gradient Protein 3; AG-3; AG3; Anterior Gradient 3 Homolog (Xenopus Laevis); Anterior Gradient Protein 3 Homolog; Anterior Gradient Homolog 3; Anterior Gradient 3 Homolog |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AGR3 |
| 全名 | Anterior Gradient 3, Protein Disulphide Isomerase Family Member |
| 背景介绍 | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016] |
| 生物功能 | Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells. [UniProt] |
| 细胞定位 | Endoplasmic reticulum. [UniProt] |
| 预测分子量 | 19 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG44619 anti-AGR3 antibody IHC-P image
Immunohistochemistry: Human gall bladder stained with ARG44619 anti-AGR3 antibody at 2 µg/mL dilution.
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ARG44619 anti-AGR3 antibody IP image
Immunoprecipitation: T-47D lysate immunoprecipitated with 2.5 µg of ARG44619 anti-AGR3 antibody.
