ARG45479
anti-AGPS antibody
anti-AGPS antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes AGPS |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AGPS |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human AGPS. |
| 偶联标记 | Un-conjugated |
| 別名 | ADHAPS; ALDHPSY; EC 2.5.1.26; ADAS; ADAP-S; Alkyldihydroxyacetonephosphate synthase, peroxisomal; Alkyl-DHAP synthase; Alkylglycerone-phosphate synthase; ADPS; Aging-associated gene 5 protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 73 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O00116 Human Alkyldihydroxyacetonephosphate synthase, peroxisomal |
|---|---|
| 基因名称 | AGPS |
| 全名 | alkylglycerone phosphate synthase |
| 背景介绍 | AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse. |
| 生物功能 | Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. [UniProt] |
| 细胞定位 | Membrane; Peroxisome. [UniProt] |
| 预测分子量 | 73 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45479 anti-AGPS antibody IHC-P image
Immunohistochemistry: Human adenocarcinoma of lung stained with ARG45479 anti-AGPS antibody at 2 μg/ml dilution.
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ARG45479 anti-AGPS antibody ICC/IF image
Immunofluorescence: SiHa stained with ARG45479 anti-AGPS antibody at 5 μg/ml dilution.
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ARG45479 anti-AGPS antibody WB image
Western blot: Hela stained with ARG45479 anti-AGPS antibody at 0.5 μg/ml dilution.
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ARG45479 anti-AGPS antibody FACS image
Flow Cytometry: U937 stained with ARG45479 anti-AGPS antibody at 1 µg/10^6 cells dilution.
