ARG40267
anti-AGL antibody
anti-AGL antibody for ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes AGL |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AGL |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 1479-1510 of Human AGL. |
| 偶联标记 | Un-conjugated |
| 別名 | Glycogen debrancher; Glycogen debranching enzyme; Oligo-1,4-1,4-glucantransferase; Amylo-1,6-glucosidase; GDE; Dextrin 6-alpha-D-glucosidase; EC 2.4.1.25; EC 3.2.1.33 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Human skeletal muscle | ||||||
| 实际分子量 | ~ 170 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AGL |
| 全名 | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| 背景介绍 | This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| 生物功能 | Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation. [UniProt] |
| 细胞定位 | Cytoplasm. Note=Under glycogenolytic conditions localizes to the nucleus. [UniProt] |
| 预测分子量 | 175 kDa |
| 翻译后修饰 | The N-terminus is blocked. Ubiquitinated. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG40267 anti-AGL antibody ICC/IF image
Immunofluorescence: HepG2 cells stained with ARG40267 anti-AGL antibody (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI (blue) for nuclear staining.
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ARG40267 anti-AGL antibody WB image
Western blot: 20 µg of Human skeletal muscle lysate stained with ARG40267 anti-AGL antibody at 1:8000 dilution.
