ARG45546
anti-ADRM1 antibody
anti-ADRM1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ADRM1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ADRM1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human ADRM1. |
| 偶联标记 | Un-conjugated |
| 別名 | ADRM1; adhesion regulating molecule 1; 110 kDa cell membrane glycoprotein; hRpn13; ARM1; ARM-1; Proteasomal ubiquitin receptor ADRM1; Gp110; Adhesion-regulating molecule 1; GP110; Rpn13 homolog; Proteasome regulatory particle non-ATPase 13 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 42 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ADRM1 |
| 全名 | adhesion regulating molecule 1 |
| 背景介绍 | This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| 生物功能 | Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus; Proteasome. [UniProt] |
| 预测分子量 | 42 kDa |
| 翻译后修饰 | Acetylation; Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (8) Click the Picture to Zoom In
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ARG45546 anti-ADRM1 antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG45546 anti-ADRM1 antibody at 2 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody ICC/IF image
Immunofluorescence: CACO-2 stained with ARG45546 anti-ADRM1 antibody at 5 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody WB image
Western blot: HEK293 stained with ARG45546 anti-ADRM1 antibody at 0.5 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody FACS image
Flow Cytometry: A431 stained with ARG45546 anti-ADRM1 antibody at 1 µg/10^6 cells dilution.
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ARG45546 anti-ADRM1 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45546 anti-ADRM1 antibody at 2 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody WB image
Western blot: Rat ovary stained with ARG45546 anti-ADRM1 antibody at 0.5 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45546 anti-ADRM1 antibody at 2 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody WB image
Western blot: RAW264.7 stained with ARG45546 anti-ADRM1 antibody at 0.5 μg/ml dilution.
