ARG44303
anti-ADNP antibody
anti-ADNP antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ADNP |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ADNP |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide |
| 偶联标记 | Un-conjugated |
| 別名 | ADNP; Activity Dependent Neuroprotector Homeobox; ADNP1; Activity-Dependent Neuroprotective Protein; KIAA0784; Activity-Dependent Neuroprotector Homeobox Protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified |
| 缓冲液 | PBS with 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9H2P0 Human Activity-dependent neuroprotector homeobox protein |
|---|---|
| 基因名称 | ADNP |
| 全名 | Activity Dependent Neuroprotector Homeobox |
| 背景介绍 | Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. |
| 生物功能 | May be involved in transcriptional regulation. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation. Positively modulates WNT-beta-catenin/CTNN1B signaling, acting by regulating phosphorylation of, and thereby stabilizing, CTNNB1. May be required for neural induction and neuronal differentiation. May be involved in erythroid differentiation. |
| 细胞定位 | Chromosome, Nucleus |
| 预测分子量 | 124 kDa |
| 翻译后修饰 | Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation |
