ARG57017
anti-ADI1 antibody [27E8]
anti-ADI1 antibody [27E8] for Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [27E8] recognizes ADI1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 27E8 |
| 同位型 | IgG1, kappa |
| 靶点名称 | ADI1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-179 of Human ADI1. |
| 偶联标记 | Un-conjugated |
| 別名 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; mtnD; SIPL; Fe-ARD; APL1; MTCBP1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; Sip-L; EC 1.13.11.54; Submergence-induced protein-like factor; MTCBP-1; ARD; Fe; 2+; Acireductone dioxygenase; Ni-ARD; HMFT1638 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9BV57 Human 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase |
|---|---|
| 基因名称 | ADI1 |
| 全名 | acireductone dioxygenase 1 |
| 背景介绍 | This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |
| 生物功能 | Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line. [UniProt] |
| 预测分子量 | 21 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG57017 anti-ADI1 antibody [27E8] WB image
Western blot: 40 µg of HepG2 cell lysate stained with ARG57017 anti-ADI1 antibody [27E8] at 1) 1:500, 2) 1:1000, and, 3) 1:5000 dilution.
