ARG58700
anti-ADAM2 antibody
anti-ADAM2 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ADAM2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ADAM2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 231-274 of Human ADAM2 (WIDENKIATTGEANELLHTFLRWKTSYLVLRPHDVAFLLVYREK). |
| 偶联标记 | Un-conjugated |
| 別名 | PH30-beta; Disintegrin and metalloproteinase domain-containing protein 2; CT15; PH30; PH-30; PH-30b; Fertilin subunit beta; ADAM 2; Cancer/testis antigen 15; FTNB; CRYN2; CRYN1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ADAM2 |
| 全名 | ADAM metallopeptidase domain 2 |
| 背景介绍 | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] |
| 生物功能 | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 82 kDa |
| 翻译后修饰 | The prodomain and the metalloprotease domain are cleaved during the epididymal maturation of the spermatozoa. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG58700 anti-ADAM2 antibody WB image
Western blot: Rat testis, Mouse testis and MCF7 whole cell lysates stained with ARG58700 anti-ADAM2 antibody at 0.5 µg/ml dilution.
