ARG43519
anti-ACTN2 antibody
anti-ACTN2 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ACTN2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ACTN2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human ACTN2. |
| 偶联标记 | Un-conjugated |
| 別名 | Acetyl-CoA carboxylase 2; ACC-beta; Biotin carboxylase; ACACB; ACC2, ACCB |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 104 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ACTN2 |
| 全名 | Actinin Alpha 2 |
| 背景介绍 | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013] |
| 生物功能 | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 104 kDa |
| 翻译后修饰 | Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG43519 anti-ACTN2 antibody WB image
Western blot: Hela and HepG2 stained with ARG43519 anti-ACTN2 antibody at 0.5 μg/ml dilution.
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ARG43519 anti-ACTN2 antibody FACS image
Flow Cytometry: A431 stained with ARG43519 anti-ACTN2 antibody at 1 µg/10^6 cells dilution.
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ARG43519 anti-ACTN2 antibody IHC-P image
Immunohistochemistry: Rat cardiac stained with ARG43519 anti-ACTN2 antibody at 2 μg/ml dilution.
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ARG43519 anti-ACTN2 antibody WB image
Western blot: Rat skeletal muscle and rat heart stained with ARG43519 anti-ACTN2 antibody at 0.5 μg/ml dilution.
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ARG43519 anti-ACTN2 antibody IHC-P image
Immunohistochemistry: Mouse cardiac stained with ARG43519 anti-ACTN2 antibody at 2 μg/ml dilution.
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ARG43519 anti-ACTN2 antibody WB image
Western blot: Mouse skeletal muscle and mouse heart stained with ARG43519 anti-ACTN2 antibody at 0.5 μg/ml dilution.
