ARG57361
anti-ACOX1 antibody
anti-ACOX1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ACOX1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ACOX1 |
| 抗原物种 | Human |
| 抗原 | Recombinant Protein of Human ACOX1. |
| 偶联标记 | Un-conjugated |
| 別名 | SCOX; Palmitoyl-CoA oxidase; Straight-chain acyl-CoA oxidase; ACOX; Peroxisomal acyl-coenzyme A oxidase 1; EC 1.3.3.6; PALMCOX; AOX |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse kidney |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ACOX1 |
| 全名 | acyl-CoA oxidase 1, palmitoyl |
| 背景介绍 | The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| 生物功能 | Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA. [UniProt] |
| 预测分子量 | 74 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG57361 anti-ACOX1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG57361 anti-ACOX1 antibody at 1:100 dilution.
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ARG57361 anti-ACOX1 antibody WB image
Western blot: Mouse kidney lysate stained with ARG57361 anti-ACOX1 antibody.
