ARG45496
anti-ACO1 / Aconitase 1 antibody
anti-ACO1 / Aconitase 1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Monkey
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ACO1 / Aconitase 1 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Mk |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ACO1 / Aconitase 1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human ACO1 / Aconitase 1. |
| 偶联标记 | Un-conjugated |
| 別名 | ACO; Aconitate hydratase 1; Aconitase 1; Citrate hydro-lyase 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 98 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ACO1 |
| 全名 | aconitase 1 |
| 背景介绍 | Encodes an aconitase that can catalyze the conversion of citrate to isocitrate through a cis-aconitate intermediate, indicating that it may participate in the TCA cycle and other primary metabolic pathways. The protein is believed to accumulate in the mitochondria and the cytosol. It affects CSD2 (At2g28190 - a superoxide dismutase) transcript levels and may play a role in the response to oxidative stress. This enzyme can also specifically bind to the 5' UTR of CSD2 in vitro. |
| 生物功能 | Catalyzes the isomerization of citrate to isocitrate via cis-aconitate; Contributes to oxidative stress tolerance. [UniProt] |
| 细胞定位 | Cytoplasm; Mitochondrion. [UniProt] |
| 预测分子量 | 98 kDa |
| 翻译后修饰 | Bifunctional iron sensor that switches between 2 activities depending on iron availability. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45496 anti-ACO1 / Aconitase1 antibody ICC/IF image
Immunofluorescence: A431 stained with ARG45496 anti-ACO1 / Aconitase1 antibody at 4 μg/ml dilution.
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ARG45496 anti-ACO1 / Aconitase1 antibody WB image
Western blot: Monkey liver stained with ARG45496 anti-ACO1 / Aconitase1 antibody at 0.5 μg/ml dilution.
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ARG45496 anti-ACO1 / Aconitase1 antibody FACS image
Flow Cytometry: SiHa stained with ARG45496 anti-ACO1 / Aconitase1 antibody at 1 µg/10^6 cells dilution.
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ARG45496 anti-ACO1 / Aconitase1 antibody IHC-P image
Immunohistochemistry: Human rectal cancer stained with ARG45496 anti-ACO1 / Aconitase1 antibody at 1 μg/ml dilution.
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ARG45496 anti-ACO1 / Aconitase1 antibody WB image
Western blot: Rat liver stained with ARG45496 anti-ACO1 / Aconitase1 antibody at 0.5 μg/ml dilution.
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ARG45496 anti-ACO1 / Aconitase1 antibody WB image
Western blot: Mouse liver stained with ARG45496 anti-ACO1 / Aconitase1 antibody at 0.5 μg/ml dilution.
