ARG56484
anti-ACADM antibody
anti-ACADM antibody for Western blot and Human,Mouse,Pig,Sheep
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ACADM |
|---|---|
| 反应物种 | Hu, Ms, Pig, Sheep |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ACADM |
| 抗原物种 | Human |
| 抗原 | Human recombinant MCAD. |
| 偶联标记 | Un-conjugated |
| 別名 | ACAD1; MCADH; EC 1.3.8.7; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ACADM |
| 全名 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| 背景介绍 | This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | This enzyme is specific for acyl chain lengths of 4 to 16. [UniProt] |
| 预测分子量 | 47 kDa |
| 翻译后修饰 | Acetylation at Lys-307 and Lys-311 in proximity of the cofactor-binding sites reduces catalytic activity (By similarity). These sites are deacetylated by SIRT3. |
