概述

产品描述	Rabbit Polyclonal antibody recognizes ACADL
反应物种	Hu, Ms, Rat
应用	IHC-P, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	ACADL
抗原物种	Human
抗原	Recombinant Protein of Human ACADL.
偶联标记	Un-conjugated
別名	ACAD4; EC 1.3.8.8; LCAD; Long-chain specific acyl-CoA dehydrogenase, mitochondrial

应用说明

应用建议	应用 推荐稀释比 IHC-P 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	SH-SY5Y

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 11363 Mouse ACADL GeneID: 25287 Rat ACADL GeneID: 33 Human ACADL Swiss-port # P15650 Rat Long-chain specific acyl-CoA dehydrogenase, mitochondrial Swiss-port # P28330 Human Long-chain specific acyl-CoA dehydrogenase, mitochondrial Swiss-port # P51174 Mouse Long-chain specific acyl-CoA dehydrogenase, mitochondrial More
基因名称	ACADL
全名	acyl-CoA dehydrogenase, long chain
背景介绍	The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008]
预测分子量	48 kDa
翻译后修饰	Acetylation at Lys-318 and Lys-322 in proximity of the cofactor-binding sites strongly reduces catalytic activity. These sites are deacetylated by SIRT3 (By similarity).

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