ARG41637
anti-ABCG1 antibody
anti-ABCG1 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ABCG1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Hm |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ABCG1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 627-647 of Human ABCG1. (ETCHFQKSEAILRELDVENAK) |
| 偶联标记 | Un-conjugated |
| 別名 | White protein homolog; WHITE1; ATP-binding cassette transporter 8; ABC8; ATP-binding cassette sub-family G member 1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | ~ 77 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P45844 Human ATP-binding cassette sub-family G member 1 |
|---|---|
| 基因名称 | ABCG1 |
| 全名 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| 背景介绍 | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008] |
| 生物功能 | Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes. [UniProt] |
| 预测分子量 | 76 kDa |
| 翻译后修饰 | Palmitoylation at Cys-315 seems important for trafficking from the endoplasmic reticulum. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG41637 anti-ABCG1 antibody WB image
Western blot: 40 µg of U87, SMMC-7721, HeLa, COLO320 and MCF7 whole cell lysates stained with ARG41637 anti-ABCG1 antibody at 0.5 µg/ml dilution.
