ARG40299
anti-ABCF1 / ABC50 antibody
anti-ABCF1 / ABC50 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ABCF1 / ABC50 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ABCF1 / ABC50 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human ABCF1. |
| 偶联标记 | Un-conjugated |
| 別名 | TNF-alpha-stimulated ABC protein; ATP-binding cassette sub-family F member 1; ABC50; ABC27; ATP-binding cassette 50 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | K562 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4),0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8NE71 Human ATP-binding cassette sub-family F member 1 |
|---|---|
| 基因名称 | ABCF1 |
| 全名 | ATP-binding cassette, sub-family F (GCN20), member 1 |
| 背景介绍 | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008] |
| 生物功能 | Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. [UniProt] |
| 细胞定位 | Isoform 2: Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope. [UniProt] |
| 预测分子量 | 96 kDa |
| 翻译后修饰 | Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2 inhibits association of EIF2 with ribosomes. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG40299 anti-ABCF1 / ABC50 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human colon stained with ARG40299 anti-ABCF1 / ABC50 antibody.
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ARG40299 anti-ABCF1 / ABC50 antibody WB image
Western blot: K562 cell lysate stained with ARG40299 anti-ABCF1 / ABC50 antibody.
