ARG64675
anti-ABCC1 / MRP1 antibody
anti-ABCC1 / MRP1 antibody for Western blot and Human
Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes ABCC1 / MRP1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog, Pig |
| 应用 | WB |
| 特异性 | This antibody is expected to recognize all reported isoforms (NP_004987.2; NP_063915.2; NP_063953.2; NP_063954.2; NP_063955.2). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ABCC1 / MRP1 |
| 抗原物种 | Human |
| 抗原 | C-HQSDLKVDENQKAYY |
| 偶联标记 | Un-conjugated |
| 別名 | GS-X; ATP-binding cassette sub-family C member 1; ABCC; Leukotriene C; ABC29; MRP; 4; LTC4 transporter; MRP1; Multidrug resistance-associated protein 1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P33527 Human Multidrug resistance-associated protein 1 |
|---|---|
| 背景介绍 | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012] |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 172 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG64675 anti-ABCC1 / MRP1 antibody WB image
Western blot: A549 lysate (35 µg protein in RIPA buffer) stained with ARG64675 anti-ABCC1 / MRP1 antibody at 0.05 µg/ml dilution.
