概述

产品描述	Rabbit Polyclonal antibody recognizes ABCB5
反应物种	Hu
应用	FACS, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	ABCB5
抗原物种	Human
抗原	KLH-conjugated synthetic peptide corresponding to aa. 1-30 (N-terminus) of Human ABCB5.
偶联标记	Un-conjugated
別名	ATP-binding cassette sub-family B member 5; ABCB5 P-gp; P-glycoprotein ABCB5; ABCB5beta; EST422562; ABCB5alpha

应用说明

应用建议	应用 推荐稀释比 FACS 1:10 - 1:50 WB 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	HL-60

属性

形式	Liquid
纯化	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
缓冲液	PBS and 0.09% (W/V) Sodium azide.
抗菌剂	0.09% (W/V) Sodium azide.
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 340273 Human ABCB5 Swiss-port # Q2M3G0 Human ATP-binding cassette sub-family B member 5
基因名称	ABCB5
全名	ATP-binding cassette, sub-family B (MDR/TAP), member 5
背景介绍	ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]
生物功能	Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair. [UniProt]
细胞定位	Cell membrane; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:12960149}
预测分子量	139 kDa

检测图片 (1) Click the Picture to Zoom In