概述

产品描述	Rabbit Polyclonal antibody recognizes ABCB11
反应物种	Hu, Ms, Rat
应用	ICC/IF, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	ABCB11
抗原物种	Human
抗原	Purified recombinant protein corresponding to amino acids 600-750 of human ABCB11
偶联标记	Un-conjugated
Protein Full name	Bile salt export pump
別名	SPGP; ABC16; BRIC2; PGY4; Bile salt export pump; PFIC2; PFIC-2; ATP-binding cassette sub-family B member 11; BSEP

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 WB 1:1000 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	HeLa; NIH3T3

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 27413 Mouse ABCB11 GeneID: 83569 Rat ABCB11 GeneID: 8647 Human ABCB11 Swiss-port # O70127 Rat Bile salt export pump Swiss-port # O95342 Human Bile salt export pump Swiss-port # Q9QY30 Mouse Bile salt export pump More
基因名称	ABCB11
全名	ATP-binding cassette, sub-family B (MDR/TAP), member 11
背景介绍	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
生物功能	Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes. [UniProt]

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