ARG45971
anti-ABCA7 antibody
anti-ABCA7 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ABCA7 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ABCA7 |
| 抗原物种 | Human |
| 抗原 | A 18 amino acid synthetic peptide within aa. 130 - 180 of human ABCA7. |
| 偶联标记 | Un-conjugated |
| 別名 | ABCA7; Autoantigen SS-N; ABCX; ATP-binding cassette sub-family A member 7; ABCA-SSN; Macrophage ABC transporter |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 240 kDa |
属性
| 纯化 | Affinity chromatography purified |
|---|---|
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8IZY2 Human ATP-binding cassette sub-family A member 7 |
|---|---|
| 基因名称 | ABCA7 |
| 全名 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| 背景介绍 | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation. [UniProt] |
| 预测分子量 | 236 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG45971 anti-ABCA7 antibody IHC-P image
Immunohistochemistry: Human spleen stained with ARG45971 anti-ABCA7 antibody.
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ARG45971 anti-ABCA7 antibody ICC/IF image
Immunofluorescence: 293 stained with ARG45971 anti-ABCA7 antibody.
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ARG45971 anti-ABCA7 antibody WB image
Western blot: 293 stained with ARG45971 anti-ABCA7 antibody.
