ARG45406
anti-AATF antibody
anti-AATF antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes AATF |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AATF |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human AATF. |
| 偶联标记 | Un-conjugated |
| 別名 | BFR2; Apoptosis-antagonizing transcription factor; CHE1; CHE-1; Rb-binding protein Che-1; Protein AATF; DED |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 95 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AATF |
| 全名 | apoptosis antagonizing transcription factor |
| 背景介绍 | The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 63 kDa |
| 翻译后修饰 | Hyperphosphorylated during the G1/S phase transition. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
-
ARG45406 anti-AATF antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45406 anti-AATF antibody at 5 μg/ml dilution.
-
ARG45406 anti-AATF antibody WB image
Western blot: 293T stained with ARG45406 anti-AATF antibody at 0.5 μg/ml dilution.
-
ARG45406 anti-AATF antibody ICC/IF image
Immunofluorescence: Rat brain stained with ARG45406 anti-AATF antibody at 5 μg/ml dilution.
-
ARG45406 anti-AATF antibody IHC-P image
Immunohistochemistry: Mouse cerebellum stained with ARG45406 anti-AATF antibody at 2 μg/ml dilution.
