概述

产品描述	Rabbit Polyclonal antibody recognizes AAK1
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	AAK1
抗原物种	Human
抗原	A 20 amino acid synthetic peptide within aa. 190 - 240 of human AAK1.
偶联标记	Un-conjugated
別名	AAK1; AP2-associated protein kinase 1; EC 2.7.11.1; Adaptor-associated kinase 1

应用说明

应用建议	应用 推荐稀释比 WB Assay-dependent
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

纯化	Affinity chromatography purified
缓冲液	PBS and 0.02% Sodium azide.
抗菌剂	0.02% Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 22848 Human AAK1 GeneID: 269774 Mouse AAK1 Swiss-port # Q2M2I8 Human AP2-associated protein kinase 1 Swiss-port # Q3UHJ0 Mouse AP2-associated protein kinase 1
基因名称	AAK1
全名	AP2 associated kinase 1
背景介绍	Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
预测分子量	104 kDa
翻译后修饰	Autophosphorylated.

检测图片 (1) Click the Picture to Zoom In