ARG64018
anti-5-HT3A Receptor antibody
anti-5-HT3A Receptor antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Metabolism antibody; Neuroscience antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes 5-HT3A Receptor |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 特异性 | This antibody is expected to recognise all three reported isoforms (NP_998786.2; NP_000860.2; NP_001155244.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | 5-HT3A Receptor |
| 抗原物种 | Human |
| 抗原 | C-GPQDFEKSPRDR |
| 偶联标记 | Un-conjugated |
| 別名 | 5-HT-3; 5-hydroxytryptamine receptor 3; Serotonin-gated ion channel receptor; 5-HT3A; 5-HT3-A; HTR3; 5HT3R; Serotonin receptor 3A; 5-hydroxytryptamine receptor 3A; 5-HT3R |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| 研究领域 | Metabolism antibody; Neuroscience antibody |
| 预测分子量 | 55 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG64018 anti-5-HT3A Receptor antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human small intestine tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64018 anti-5-HT3A Receptor antibody at 3.75 µg/ml dilution followed by AP-staining.
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ARG64018 anti-5-HT3A Receptor antibody WB image
Western blot: 35 µg of Human Colon lysate (in RIPA buffer) stained with ARG64018 anti-5-HT3A Receptor antibody at 0.3 µg/ml dilution and incubated at RT for 1 hour.
