ARG82627
Soluble Collagen Assay Kit
Soluble Collagen Assay 试剂盒 for Functional study and All
概述
| 产品描述 | ARG82627 Soluble Collagen Assay Kit is a detection kit for the quantification of soluble or solubilized collagens in tissue culture supernatants, cellular extracts and tissue homogenates. |
|---|---|
| 反应物种 | All |
| 应用 | FuncSt |
| 特异性 | Measures all types of fibrillar collagen, species independent. |
| 靶点名称 | Collagen |
| 偶联标记说明 | Read at 540 nm. |
| 检测范围 | 0.5 - 10 µg/well (3.5 - 70 µg/ml) |
| 样品类型 | Tissue culture supernatants, cellular extracts and tissue homogenates. |
| 样本量 | 140 µl |
| 別名 | OI1; OI2; OI3; OI4; EDSC; Collagen alpha-1(I) chain; Alpha-1 type I collagen |
应用说明
| 检测时间 | < 3 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | COL1A1 |
|---|---|
| 全名 | collagen, type I, alpha 1 |
| 背景介绍 | This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008] |
| 生物功能 | Type I collagen is a member of group I collagen (fibrillar forming collagen). [UniProt] |
| 细胞定位 | Secreted, extracellular space, extracellular matrix. [UniProt] |
| 产品亮点 | Related products: Collagen antibodies; Collagen ELISA Kits; Collagen Duos / Panels; Collagen recombinant proteins; Related news: New antibody panels for Myofibroblasts and CAFs |
| 翻译后修饰 | Proline residues at the third position of the tripeptide repeating unit (G-X-P) are hydroxylated in some or all of the chains. Proline residues at the second position of the tripeptide repeating unit (G-P-X) are hydroxylated in some of the chains. O-linked glycan consists of a Glc-Gal disaccharide bound to the oxygen atom of a post-translationally added hydroxyl group. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG82627 Soluble Collagen Assay Kit typical data demonstration image
ARG82627 Soluble Collagen Assay Kit results of a typical data with optical density reading at 540 nm.
| Title | Download Link |
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| ARG82627 Soluble Collagen Assay Kit User manual |
 Download
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