ARG81189

Rat alpha 2 Macroglobulin ELISA Kit

Rat alpha 2 Macroglobulin ELISA 试剂盒 for ELISA and Rat

概述

产品描述 ARG81189 Rat Alpha-2-Macroglobulin ELISA is an Enzyme Immunoassay kit for the quantification of Rat Alpha-2-Macroglobulin in serum, plasma, cell culture and urine.
反应物种 Rat
应用 ELISA
靶点名称 alpha 2 Macroglobulin
偶联标记 HRP
偶联标记说明 Substrate: TMB and read at 450 nm
灵敏度 less than 0.1 ng/ml
样品类型 Serum, plasma, cell culture and urine.
标准范围 0.156 - 10 ng/ml
样本量 50 µl
別名 CPAMD5; Alpha-2-macroglobulin; S863-7; FWP007; Alpha-2-M; A2MD; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5

应用说明

检测时间 ~ 4 hours

属性

形式 96 well
存放说明 Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 24153 Rat A2M

Swiss-port # P06238 Rat Alpha-2-macroglobulin

基因名称 A2m
全名 alpha-2-macroglobulin
背景介绍 Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008]
生物功能 Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase. [UniProt]
产品亮点 Related products:
alpha-2-Macroglobulin antibodies; alpha-2-Macroglobulin ELISA Kits;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData

检测图片 (1) Click the Picture to Zoom In

  • ARG81189 Rat Alpha-2-Macroglobulin ELISA Kit standard curve image

    ARG81189 Rat Alpha-2-Macroglobulin ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG81189 Rat Alpha-2-Macroglobulin ELISA Kit User's manual download icon Download