ARG83482

Rat Antithrombin III ELISA Kit

Rat Antithrombin III ELISA 试剂盒 for ELISA and Rat

概述

产品描述 ARG83482 Rat Antithrombin III ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rat Antithrombin III in Plasma, Serum and Urine
反应物种 Rat
应用 ELISA
靶点名称 Antithrombin III
偶联标记 HRP
偶联标记说明 Substrate: TMB and read at 450 nm.
灵敏度 6.25 ng/ml
样品类型 Plasma, Serum and Urine
标准范围 12.5 - 400 ng/ml
样本量 100 µl
精确 Intra-Assay CV: less than 10%
Inter-Assay CV: less than 10%
別名 SERPINC1; Serpin Family C Member 1; ATIII; AT3; Serine (Or Cysteine) Proteinase Inhibitor, Clade C (Antithrombin), Member 1; Serpin Peptidase Inhibitor, Clade C (Antithrombin), Member 1; Antithrombin-III; MGC22579; Coding Sequence Signal Peptide Antithrombin Part 1; Serpin Peptidase Inhibitor Clade C Member 1; Signal Peptide Antithrombin Part 1; Antithrombin (Aa 375-432); Antithrombin III; Serpin C1; ATIII-R2; ATIII-T1; ATIII-T2; THPH7; AT3D

应用说明

检测时间 2 hours

属性

形式 96 well
存放说明 Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称 SERPINC1
全名 serpin peptidase inhibitor, clade C (antithrombin), member 1
背景介绍 The protein encoded by this gene, antithrombin III, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. Numerous mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency which constitutes a strong risk factor for thrombosis. A reduction in the serum level of this protein is associated with severe cases of Coronavirus Disease 19 (COVID-19).
生物功能 Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade.
细胞定位 Secreted
翻译后修饰 Disulfide bond, Glycoprotein, Phosphoprotein
Title Download Link
ARG83482 Rat Antithrombin III ELISA Kit User manual download icon Download