ARG83214
Rabbit GREM2 ELISA Kit
Rabbit GREM2 ELISA 试剂盒 for ELISA and Rabbit
概述
| 产品描述 | ARG83214 Rabbit GREM2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rabbit GREM2 in Serum, Plasma and Cell culture supernatants. |
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| 反应物种 | Rb |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | GREM2 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 15 pg/ml |
| 检测范围 | 62.5 pg/ml - 4,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 4.5% Inter-Assay CV: 7.8% |
| 別名 | PRDC; Gremlin-2; DAND3; Protein related to DAN and cerberus; CKTSF1B2; DAN domain family member 3; Cysteine knot superfamily 1, BMP antagonist 2 |
应用说明
| 检测时间 | ~ 5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | GREM2 |
|---|---|
| 全名 | gremlin 2, DAN family BMP antagonist |
| 背景介绍 | This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008] |
| 生物功能 | Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells (By similarity). [UniProt] |
| 产品亮点 | Related products: GREM2 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | N-glycosylated. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG83214 Rabbit GREM2 ELISA Kit standard curve image
ARG83214 Rabbit GREM2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83214 Rabbit GREM2 ELISA Kit User manual |
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