ARG83380

Pyrimidine Dimer ELISA Kit

Pyrimidine Dimer ELISA 试剂盒 for ELISA and Other

DNA, MutationDimers (chemistry), DNA replication and repair-deficiency disorders, Senescence, Cyclobutanes

概述

产品描述 ARG83380 Pyrimidine Dimers ELISA Kit is an Enzyme Immunoassay kit for the quantification of Pyrimidine Dimer in Cell / Tissue genomic DNA
反应物种 Other
应用 ELISA
靶点名称 Pyrimidine Dimer
偶联标记 HRP
偶联标记说明 Read at 450 nm.
灵敏度 0.8 ng/mL
样品类型 Cell / Tissue genomic DNA
标准范围 1.56 - 100 ng/mL
样本量 50 µL

应用说明

检测时间 ~3.5 hours

属性

形式 96 well
存放说明 Store components at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

背景介绍 Absorption of ultraviolet (UV) light produces two predominant types of DNA damage, cyclobutane pyrimidine dimers and pyrimidine pyrimidone photoproducts. The result is a transition of C to T and CC to TT, which are the most frequent mutations of p53 in both human and mouse skin cancers. UV damaged DNA is usually repaired by nucleotide excision repair or base excision repair. After UV exposure, cells activate p53 and stall the cell cycle for repair. If the damage is too severe, the cell will trigger apoptosis to get rid of DNA damaged, potentially mutant cells.
研究领域 DNA, MutationDimers (chemistry), DNA replication and repair-deficiency disorders, Senescence, Cyclobutanes

检测图片 (1) Click the Picture to Zoom In

  • ARG83380 Pyrimidine Dimer ELISA Kit standard curve image

    ARG83380 Pyrimidine Dimer ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
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