ARG82188

Peroxidase Activity Assay Kit (Colorimetric)

Peroxidase Activity Assay 试剂盒 (Colorimetric) for Functional study and Human,Mouse,Rat,All

概述

产品描述 ARG82188 Peroxidase Activity Assay Kit (Colorimetric) can be used to measure Peroxidase activity in serum, plasma, urine, tissue and cell culture supernatants.
反应物种 Hu, Ms, Rat, All
应用 FuncSt
靶点名称 Peroxidase
偶联标记说明 Read at 570 nm (colorimetric), or 530/585 nm (fluorometric)
灵敏度 4 U/L (colorimetric); 0.8 U/L (fluorometric)
检测范围 2 - 50 U/L (colorimetric); 0.1 - 5 U/L (fluorometric)
样品类型 serum, plasma, urine, tissue and cell culture supernatants
样本量 10 µl
別名 TPO; EC 1.11.1.8; TDH2A; Thyroid peroxidase; MSA; TPX

应用说明

应用说明 Please note that this kit does not include a microplate.
检测时间 20 min

属性

形式 Liquid
存放说明 Store the kit at -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 22018 Mouse TPO

GeneID: 7173 Human TPO

Swiss-port # P07202 Human Thyroid peroxidase

Swiss-port # P35419 Mouse Thyroid peroxidase

基因名称 TPO
全名 thyroid peroxidase
背景介绍 This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
生物功能 Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). [UniProt]
细胞定位 Membrane; Single-pass type I membrane protein. Isoform 3: Cell surface. [UniProt]
翻译后修饰 Glycosylated.

Heme is covalently bound through a H(2)O(2)-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface.

Cleaved in its N-terminal part. [UniProt]

检测图片 (1) Click the Picture to Zoom In

  • ARG82188 Peroxidase Activity Assay Kit (Colorimetric) typical data demonstration image

    ARG82188 Peroxidase Activity Assay Kit (Colorimetric) results of a typical data with optical density reading at 570 nm.

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