ARG81250

Mouse/Rat PDGF BB ELISA Kit

Mouse/Rat PDGF BB ELISA 试剂盒 for ELISA and Mouse,Rat

概述

产品描述 ARG81250 Mouse/Rat PDGF BB ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse/Rat PDGF BB in serum, plasma or cell culture supernatants.
反应物种 Ms, Rat
应用 ELISA
靶点名称 PDGF BB
偶联标记 HRP
偶联标记说明

Substrate: TMB and read at 450 nm.

灵敏度 30 pg/ml
样品类型 Serum, plasma or cell culture supernatants.
标准范围 62.5 - 4000 pg/ml
样本量 100 µl
別名 SIS; Becaplermin; Platelet-derived growth factor subunit B; IBGC5; PDGF subunit B; c-sis; SSV; PDGF-2; Proto-oncogene c-Sis; Platelet-derived growth factor beta polypeptide; PDGF2; Platelet-derived growth factor B chain

应用说明

检测时间 ~ 3.5 hours

属性

形式 96 well
存放说明 Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 18591 Mouse PDGFB

GeneID: 24628 Rat PDGFB

Swiss-port # P31240 Mouse Platelet-derived growth factor subunit B

Swiss-port # Q05028 Rat Platelet-derived growth factor subunit B

基因名称 Pdgfb
全名 platelet derived growth factor, B polypeptide
背景介绍 The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013]
生物功能 Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity). [UniProt]
产品亮点 Related products:
PDGF BB antibodies; PDGF BB ELISA Kits;
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New ELISA data calculation tool:
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检测图片 (1) Click the Picture to Zoom In

  • ARG81250 Mouse/Rat PDGF BB ELISA Kit standard curve image

    ARG81250 Mouse/Rat PDGF BB ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG81250 Mouse/Rat PDGF-BB ELISA Kit User's manual download icon Download