ARG83628
Mouse IL2 ELISA Kit
Mouse IL2 ELISA 试剂盒 for ELISA and Mouse
概述
| 产品描述 | ARG83628 Mouse IL2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse IL2 in serum, plasma and cell culture supernatants. |
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| 反应物种 | Ms |
| 应用 | ELISA |
| 靶点名称 | IL2 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 7.8125 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 15.625 - 1000 pg/ml |
| 样本量 | 50 µl |
| 精确 | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| 別名 | IL2; Interleukin 2; IL-2; TCGF; T Cell Growth Factor; Interleukin-2; Aldesleukin; Involved In Regulation Of T-Cell Clonal Expansion; T-Cell Growth Factor; Lymphokine |
应用说明
| 检测时间 | 4 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | IL2 |
|---|---|
| 全名 | Interleukin 2 |
| 背景介绍 | This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Sep 2020] |
| 生物功能 | Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance. Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG83628 Mouse IL2 ELISA Kit standard curve image
ARG83628 Mouse IL2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83628 Mouse IL2 ELISA Kit User manual |
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