ARG83222
Mouse DLL1 ELISA Kit
Mouse DLL1 ELISA 试剂盒 for ELISA and Mouse
概述
产品描述 | ARG83222 Mouse DLL1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse DLL1 in Serum, Plasma and Cell culture supernatants. |
---|---|
反应物种 | Ms |
应用 | ELISA |
特异性 | There is no detectable cross-reactivity with other relevant proteins. |
靶点名称 | DLL1 |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
灵敏度 | 15 pg/ml |
检测范围 | 31.2 pg/ml - 2,000 pg/ml |
样品类型 | Serum, Plasma and Cell culture supernatants |
精确 | Intra-Assay CV: 5.2% Inter-Assay CV: 6.2% |
別名 | DELTA1; H-Delta-1; Drosophila Delta homolog 1; Delta-like protein 1; DL1; Delta1; Delta |
应用说明
检测时间 | ~ 5 hours |
---|
属性
形式 | 96 well |
---|---|
存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
---|---|
基因名称 | DLL1 |
全名 | delta-like 1 (Drosophila) |
背景介绍 | DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008] |
生物功能 | Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. [UniProt] |
产品亮点 | Related products: DLL1 antibodies; DLL1 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
翻译后修饰 | Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation (By similarity). Ubiquitinated; promotes recycling back to the plasma membrane and confers a strong affinity for NOTCH1. Multi-ubiquitination of LYS-613 by MIB1 promotes both cis and trans-interaction with NOTCH1, as well as activation of Notch signaling. Ubiquitinated by NEURL1B (By similarity). Phosphorylated in a membrane association-dependent manner. Phosphorylation at Ser-697 requires the presence of Ser-694, whereas phosphorylation at Ser-694 occurs independently of the other site. Phosphorylation is required for full ligand activity in vitro and affects surface presentation, ectodomain shedding, and endocytosis. O-fucosylated. Can be elongated to a disaccharide by MFNG. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
Title | Download Link |
---|---|
ARG83222 Mouse DLL1 ELISA Kit User manual |
![]() |