ARG83220
Mouse Cathepsin E ELISA Kit
Mouse Cathepsin E ELISA 试剂盒 for ELISA and Mouse
概述
| 产品描述 | ARG83220 Mouse Cathepsin E ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse Cathepsin E in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | Cathepsin E |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 25 pg/ml |
| 检测范围 | 156 pg/ml - 10,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 4.5% Inter-Assay CV: 4.8% |
| 別名 | EC 3.4.23.34; CATE; Cathepsin E |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CTSE |
| 全名 | cathepsin E |
| 背景介绍 | This gene encodes a member of the A1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme, an aspartic endopeptidase, may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of this gene has been observed in neurodegeneration. [provided by RefSeq, Nov 2015] |
| 生物功能 | May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. [UniProt] |
| 细胞定位 | Endosome. Note=The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome. [UniProt] |
| 翻译后修饰 | Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide. Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
-
ARG83220 Mouse Cathepsin E ELISA Kit standard curve image
ARG83220 Mouse Cathepsin E ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG83220 Mouse Cathepsin E ELISA Kit User manual |
 Download
|
