ARG70590

Mouse Cadherin 17 recombinant protein (His-tagged, C-ter)

Mouse Cadherin 17 recombinant protein (His-tagged, C-ter) for SDS-PAGE

概述

产品描述 CHO expressed, His-tagged (C-ter) Mouse Cadherin 17 recombinant protein
应用 SDS-PAGE
靶点名称 Cadherin 17
物种 Mouse
A.A. 序列 Phe26 - Met786
表达系统 CHO
別名 CDH17; cadherin 17, LI cadherin (liver-intestine); CDH16; Cadherin-17; HPT-1; HPT1; Intestinal peptide-associated transporter HPT-1; LI-cadherin; Liver-intestine cadherin

属性

形式 Powder
纯化说明 Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test.
纯度 > 95% (by SDS-PAGE)
缓冲液 PBS (pH 7.4)
复溶 It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
存放说明 For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称 CDH17
全名 cadherin 17, LI cadherin (liver-intestine)
背景介绍 This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
生物功能 Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. [UniProt]
细胞定位 Cell membrane; Single-pass type I membrane protein. [UniProt]
产品亮点 Related products:
Cadherin antibodies; Cadherin ELISA Kits; Cadherin Duos / Panels;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
翻译后修饰 Glycoprotein. [UniProt]