ARG70433
Mouse CCL3 / MIP1 alpha recombinant protein (Active) (His-tagged, N-ter)
Mouse CCL3 / MIP1 alpha recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE
概述
| 产品描述 | E. coli expressed, His-tagged (N-ter) Active Mouse CCL3 / MIP1 alpha recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | CCL3 / MIP1 alpha |
| 物种 | Mouse |
| A.A. 序列 | Ala24 - Ala92 |
| 表达系统 | E. coli |
| Protein Full name | C-C motif chemokine 3 |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to chemoattract human PBMCs using a concentration range of 10.0 - 100.0 ng/mL. Note: Results may vary from different PBMC donors. |
| 別名 | CCL3; C-C Motif Chemokine Ligand 3; MIP-1-Alpha; G0S19-1; LD78ALPHA; SCYA3; Small Inducible Cytokine A3 (Homologous To Mouse Mip-1a); Macrophage Inflammatory Protein 1-Alpha |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CCL3 |
|---|---|
| 全名 | C-C Motif Chemokine Ligand 3 |
| 背景介绍 | This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1. |
| 生物功能 | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| 细胞定位 | Secreted |
| 翻译后修饰 | Disulfide bond |
检测图片 (1) Click the Picture to Zoom In
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ARG70433 Mouse CCL3 / MIP1 alpha recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70433 Mouse CCL3 / MIP1 alpha recombinant protein (Active) (His-tagged, N-ter)
