ARG82915
Human Urokinase / uPA ELISA Kit
Human Urokinase / uPA ELISA 试剂盒 for ELISA and Human
概述
产品描述 | ARG82915 Human Urokinase / uPA ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Urokinase / uPA in serum, plasma (heparin, EDTA), cell lysates and cell culture supernatants. |
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反应物种 | Hu |
应用 | ELISA |
靶点名称 | Urokinase / uPA |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
灵敏度 | 10 pg/ml |
样品类型 | Serum, plasma (heparin, EDTA), cell lysates and cell culture supernatants. |
标准范围 | 62.5 - 4000 pg/ml |
样本量 | 100 μl |
精确 | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
別名 | PLAU; Plasminogen Activator, Urokinase; UPA; URK; Urokinase-Type Plasminogen Activator; U-Plasminogen Activator; EC 3.4.21.73; Plasminogen Activator, Urinary; EC 3.4.21; BDPLT5; U-PA; ATF; QPD |
应用说明
检测时间 | 4 hours |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 |
Swiss-port # P00749 Human Urokinase-type plasminogen activator |
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基因名称 | PLAU |
全名 | Plasminogen Activator, Urokinase |
背景介绍 | This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
生物功能 | Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. [Uniprot] |
细胞定位 | Secreted. [Uniprot] |
翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein, Zymogen. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
Title | Download Link |
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ARG82915 Human Urokinase / uPA ELISA Kit User manual |
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