ARG81247
Human S100 beta ELISA Kit
Human S100 beta ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG81247 Human S100 beta ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human S100 beta in serum and plasma. |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | No cross-reactivity to the following recombinant human proteins: Adiponectin, BMP1, BMP2, BMP4, BMP7, CRP, CCL2, CCL4, CCL5, HGF, HSP27, IGF-1, IL1β, IL2, IL4, IL5, IL6, IL8, IL12, IL13, IL15, IL17C, IL21, IFNγ, PDGF, PLA2G7, serpin E1, TGFβ1, TGFβ2, TGFβ3, TLR1, TLR2, TLR3, TLR9, TNF-α, TNF RI, TNF RII, VEGF, VEGF R1. |
| 靶点名称 | S100 beta |
| 偶联标记 | HRP |
| 偶联标记说明 | Read at 450 nm |
| 灵敏度 | 10 pg/ml |
| 样品类型 | Serum, plasma and Cell culture supernatants. |
| 标准范围 | 62.5 - 4000 pg/ml |
| 样本量 | 100 µl |
| 別名 | S-100 protein beta chain; NEF; S100; Protein S100-B; S100 calcium-binding protein B; S100beta; S-100 protein subunit beta; S100-B |
应用说明
| 检测时间 | ~ 3 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
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| 基因名称 | S100B |
| 全名 | S100 calcium binding protein B |
| 背景介绍 | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008] |
| 生物功能 | Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity. [UniProt] |
| 产品亮点 | Related products: S100 beta antibodies; S100 beta ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
检测图片 (1) Click the Picture to Zoom In
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ARG81247 Human S100 beta ELISA Kit standard curve image
ARG81247 Human S100 beta ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG81247 Human S100 beta ELISA Kit User's manual |
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