ARG83750

Human Perforin ELISA Kit

Human Perforin ELISA 试剂盒 for ELISA and Human

概述

产品描述 ARG83750 Human Perforin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Perforin in serum, plasma and cell culture supernatants.
反应物种 Hu
应用 ELISA
靶点名称 Perforin
偶联标记 HRP
偶联标记说明 Substrate: TMB and read at 450 nm.
灵敏度 46.88 pg/ml
样品类型 Serum, plasma and cell culture supernatants.
标准范围 93.75 - 6000 pg/ml
样本量 50 µl
精确 Intra-Assay CV: <10%
Inter-Assay CV: <10%
別名 PRF1; Perforin 1; PFP; P1; HPLH2; Perforin 1 (Pore Forming Protein); Lymphocyte Pore-Forming Protein; Perforin-1; Cytolysin; Perforin 1 (Preforming Protein); Perforin

应用说明

检测时间 4 hours

属性

形式 96 well
存放说明 Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 5551 Human PRF1

Swiss-port # P14222 Human Perforin-1

基因名称 PRF1
全名 Perforin 1
背景介绍 This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
生物功能 Perforin pores allow the release of mature caspase-7 (CASP7) into the extracellular milieu. [Uniprot]
翻译后修饰 Disulfide bond, Glycoprotein. [Uniprot]

检测图片 (1) Click the Picture to Zoom In

  • ARG83750 Human Perforin ELISA Kit standard curve image

    ARG83750 Human Perforin ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG83750 Human Perforin ELISA Kit User manual download icon Download