ARG82594
Human OSMR ELISA Kit
Human OSMR ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG82594 Human OSMR ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human OSMR in serum, plasma and cell culture supernatants. |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | This kit could assay both natural and recombinant Human OSMR. No significant cross-reactivity or interference was observed in the following samples: Human: IFN gamma, IL1 beta, IL2, IL4, IL5, IL6, IL8, IL10, IL12, IL17A, IL18, IL21, IL22, IL23, MCP1, TGF beta 1, TNF alpha and VEGF. Mouse: GM-CSF, IFN gamma, IL1 beta, IL2, IL4, IL6, IL10, IL17A and TNF alpha. Rat: IFN gamma, IL1 beta, IL4, IL6, IL10 and TNF alpha. |
| 靶点名称 | OSMR |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 0.12 ng/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 0.23 - 15 ng/ml |
| 样本量 | 10 - 100 µl |
| 精确 | Intra-Assay CV: 3.1% Inter-Assay CV: 2.5% |
| 別名 | OSMRB; IL-31RB; Oncostatin-M-specific receptor subunit beta; Interleukin-31 receptor subunit beta; IL-31 receptor subunit beta; PLCA1; IL-31R-beta; IL-31R subunit beta |
应用说明
| 检测时间 | ~ 3.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q99650 Human Oncostatin-M-specific receptor subunit beta |
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| 基因名称 | OSMR |
| 全名 | oncostatin M receptor |
| 背景介绍 | This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
| 生物功能 | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 产品亮点 | Related products: New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
检测图片 (1) Click the Picture to Zoom In
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ARG82594 Human OSMR ELISA Kit standard curve image
ARG82594 Human OSMR ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG82594 Human OSMR ELISA Kit User manual |
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