ARG83660
Human NUDT5 ELISA Kit
Human NUDT5 ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG83660 Human NUDT5 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human NUDT5 in Serum, plasma (heparin, EDTA) and cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | NUDT5 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 50 pg/ml |
| 样品类型 | Serum, plasma (heparin, EDTA) and cell culture supernatants. |
| 标准范围 | 93.7 - 6000 pg/ml |
| 样本量 | 100 μl |
| 精确 | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| 別名 | NUDT5; Nudix Hydrolase 5; YSA1H; Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5; Nuclear ATP-Synthesis Protein NUDIX5; ADP-Sugar Pyrophosphatase; 8-Oxo-DGDP Phosphatase; HYSAH1; HNUDT5; Nucleoside Diphosphate-Linked Moiety X Motif 5; Nudix Motif 5; EC 3.6.1.13; EC 3.6.1.58; EC 2.7.7.96; NUDIX5; YSAH1; YSA1 |
应用说明
| 检测时间 | 4 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NUDT5 |
| 全名 | Nudix Hydrolase 5 |
| 背景介绍 | This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. |
| 生物功能 | Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate. [Uniprot] |
| 细胞定位 | Nucleus. [Uniprot] |
| 翻译后修饰 | Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG83660 Human NUDT5 ELISA Kit standard curve image
ARG83660 Human NUDT5 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG83660 Human NUDT5 ELISA Kit User manual |
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