ARG83668
Human NQO1 ELISA Kit
Human NQO1 ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG83668 Human NQO1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human NQO1 in Serum, plasma (heparin, EDTA) and cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | NQO1 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 10 pg/ml |
| 样品类型 | Serum, plasma (heparin, EDTA) and cell culture supernatants. |
| 标准范围 | 15.6 - 1000 pg/ml |
| 样本量 | 100 μl |
| 精确 | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| 別名 | NQO1; NAD(P)H Quinone Dehydrogenase 1; QR1; DTD; DT-Diaphorase; NMOR1; DHQU; DIA4; Diaphorase (NADH/NADPH) (Cytochrome B-5 Reductase); NAD(P)H Dehydrogenase [Quinone] 1; NAD(P)H Dehydrogenase, Quinone 1; NAD(P)H:Quinone Oxidoreductase 1; NAD(P)H-Quinone Oxidoreductase; Phylloquinone Reductase; Menadione Reductase; Quinone Reductase 1; Azoreductase; EC 1.6.5.2; NAD(P)H:Quinone Acceptor Oxidoreductase Type 1; NAD(P)H:Menadione Oxidoreductase 1; NAD(P)H:Quinone Oxireductase; Dioxin-Inducible 1; Quinone Reductase; Diaphorase-4; NMORI |
应用说明
| 检测时间 | 4 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NQO1 |
| 全名 | NAD(P)H Quinone Dehydrogenase 1 |
| 背景介绍 | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | Acts as a gatekeeper of the core 20S proteasome known to degrade proteins with unstructured regions. Upon oxidative stress, interacts with tumor suppressors TP53 and TP73 in a NADH-dependent way and inhibits their ubiquitin-independent degradation by the 20S proteasome. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG83668 Human NQO1 ELISA Kit standard curve image
ARG83668 Human NQO1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83668 Human NQO1 ELISA Kit User manual |
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