ARG82291
Human M-CSF ELISA Kit
Human M-CSF ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG82291 Human M-CSF ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human M-CSF in serum, plasma and cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Not react with Human SCF and rarely react with Mouse M-CSF. |
| 靶点名称 | M-CSF |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 7.8 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 15.6 - 1000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: less than 8.5% Inter-Assay CV: less than 8.5% |
| 別名 | Macrophage colony-stimulating factor 1; CSF-1; Lanimostim; M-CSF; MCSF |
应用说明
| 检测时间 | ~ 3.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P09603 Human Macrophage colony-stimulating factor 1 |
|---|---|
| 基因名称 | CSF1 |
| 全名 | colony stimulating factor 1 (macrophage) |
| 背景介绍 | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] |
| 生物功能 | Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type I membrane protein. Processed macrophage colony-stimulating factor 1: Secreted, extracellular space. [UniProt] |
| 产品亮点 | Related products: M-CSF antibodies; M-CSF ELISA Kits; M-CSF recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | N- and O-glycosylated. Glycosylation and proteolytic cleavage yield different soluble forms. One high molecular weight soluble form is a proteoglycan containing chondroitin sulfate. O-glycosylated with core 1 or possibly core 8 glycans. Isoform 1 is N- and O-glycosylated. Isoform 3 is only N-glycosylated. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG82291 Human M-CSF ELISA Kit standard curve image
ARG82291 Human M-CSF ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG82291 Human M-CSF ELISA kit User's manual |
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