ARG81464
Human Klk6 / neurosin ELISA Kit
Human Klk6 / neurosin ELISA 试剂盒 for ELISA and Human
内含物
| 货号 | 内含物名称 | 包装 | 温度 |
|---|---|---|---|
| ARG81464-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG81464-002 | Standard | 2 X 10 ng/vial | 4°C |
| ARG81464-003 | Standard/Sample diluent | 30 ml (Ready to use) | 4°C |
| ARG81464-004 | Antibody conjugate concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81464-005 | Antibody diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81464-006 | HRP-Streptavidin concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81464-007 | HRP-Streptavidin diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81464-008 | 25X Wash buffer | 20 ml | 4°C |
| ARG81464-009 | TMB substrate | 10 ml (Ready to use) | 4°C (Protect from light) |
| ARG81464-010 | STOP solution | 10 ml (Ready to use) | 4°C |
| ARG81464-011 | Plate sealer | 4 strips | Room temperature |
概述
| 产品描述 | ARG81464 Human Klk6 / neurosin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Klk6 / neurosin in serum, plasma (heparin, EDTA) and cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | Klk6 / neurosin |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 39 pg/ml |
| 样品类型 | Serum, plasma (heparin, EDTA) and cell culture supernatants. |
| 标准范围 | 78 - 5000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: 6.1% Inter-Assay CV: 7.2% |
| 別名 | PRSS18; Serine protease 9; Kallikrein-6; Klk7; hK6; Neurosin; Bssp; Protease M; EC 3.4.21.-; SP59; PRSS9; Zyme; Serine protease 18 |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KLK6 |
| 全名 | kallikrein-related peptidase 6 |
| 背景介绍 | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis. [UniProt] |
| 产品亮点 | Related products: KLK antibodies; KLK ELISA Kits; KLK Duos / Panels; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Inactivated by autolytic cleavage after Arg-80. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG81464 Human Klk6 / neurosin ELISA Kit standard curve image
ARG81464 Human Klk6 / neurosin ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG81464 Human Klk6 / neurosin ELISA Kit User manual |
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