ARG70516
Human Kallikrein 2 recombinant protein (His-tagged)
Human Kallikrein 2 recombinant protein (His-tagged) for SDS-PAGE
概述
| 产品描述 | CHO expressed, His-tagged Human Kallikrein 2 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | Kallikrein 2 |
| A.A. 序列 | Met1 - Pro261 |
| 表达系统 | CHO |
| 別名 | KLK2; Kallikrein Related Peptidase 2; Kallikrein 2, Prostatic; Glandular Kallikrein-1; Tissue Kallikrein-2; Kallikrein-2; HGK-1; Glandular Kallikrein 2; EC 3.4.21.35; EC 3.4.21; KLK2A2; HK2 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 80% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/ml and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | KLK2 |
|---|---|
| 全名 | Kallikrein Related Peptidase 2 |
| 背景介绍 | This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012] |
| 生物功能 | Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. [Uniprot] |
